RBP4 Antibody (monoclonal) (M05)
Mouse monoclonal antibody raised against a full length recombinant RBP4.
|Application ||WB, IHC, E|
|Calculated MW||23010 Da|
|Other Names||Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176), RBP4|
|Target/Specificity||RBP4 (AAH20633.1, 19 a.a. ~ 201 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||RBP4 Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
[Expression and regulation of retinol binding protein 4 mRNA in human adipose tissue in obese and type 2 diabetics] Liu XH, et al. Zhonghua Yi Xue Za Zhi, 2010 May 11. PMID 20646597.Case-control analysis of SNPs in GLUT4, RBP4 and STRA6: association of SNPs in STRA6 with type 2 diabetes in a South Indian population. Nair AK, et al. PLoS One, 2010 Jul 6. PMID 20625434.Decreased retinol binding protein 4 concentrations are associated with cholesterol gallstone disease. Wang SN, et al. J Formos Med Assoc, 2010 Jun. PMID 20610143.Retinol-binding protein 4 levels in obese children and adolescents with glucose intolerance. Yeste D, et al. Horm Res Paediatr, 2010. PMID 20389103.Association of plasma retinol-binding protein 4, adiponectin, and high molecular weight adiponectin with insulin resistance in non-diabetic hypertensive patients. Shim CY, et al. Yonsei Med J, 2010 May. PMID 20376890.
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