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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   REN Antibody (monoclonal) (M01)   

REN Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant REN.

  • WB - REN Antibody (monoclonal) (M01) AT3617a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (67.87 KDa) .
  • WB - REN Antibody (monoclonal) (M01) AT3617a
    REN monoclonal antibody (M01), clone 2H2 Western Blot analysis of REN expression in K-562 ( (Cat # AT3617a )
  • E - REN Antibody (monoclonal) (M01) AT3617a
    Detection limit for recombinant GST tagged REN is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P00797
Other Accession BC047752
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 2H2
Calculated MW 45057 Da
Additional Information
Gene ID 5972
Other Names Renin, Angiotensinogenase, REN
Target/Specificity REN (AAH47752, 24 a.a. ~ 406 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsREN Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.


1.HIV-induced kidney cell injury: role of ROS-induced downregulated vitamin D receptor.Salhan D, Husain M, Subrati A, Goyal R, Singh T, Rai P, Malhotra A, Singhal PC.Am J Physiol Renal Physiol. 2012 Aug;303(4):F503-14. Epub 2012 May 30.

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$ 315.00
Cat# AT3617a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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