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RHOH Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a full length recombinant RHOH.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q15669 |
| Other Accession | BC014261 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3D3 |
| Calculated MW | 21331 Da |
| Gene ID | 399 |
|---|---|
| Other Names | Rho-related GTP-binding protein RhoH, GTP-binding protein TTF, Translocation three four protein, RHOH, ARHH, TTF |
| Target/Specificity | RHOH (AAH14261.1, 1 a.a. ~ 191 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RHOH Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the Ras superfamily of small GTPases. Expression of a chimeric transcript of LAZ3 and this gene has been reported as a result of the translocation t(3;4) in non-Hodgkin's lymphomas. This gene encodes a small G-like protein, and unlike most other small G proteins which are expressed ubiquitously, this gene is transcribed only in hemopoietic cells.
References
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Lysosomal degradation of RhoH protein upon antigen receptor activation in T but not B cells. Schmidt-Mende J, et al. Eur J Immunol, 2010 Feb. PMID 19950172.Involvement of RhoH GTPase in the development of B-cell chronic lymphocytic leukemia. Sanchez-Aguilera A, et al. Leukemia, 2010 Jan. PMID 19847197.RhoH/TTF negatively regulates leukotriene production in neutrophils. Daryadel A, et al. J Immunol, 2009 May 15. PMID 19414807.Prognostic implication and biological roles of RhoH in acute myeloid leukaemia. Iwasaki T, et al. Eur J Haematol, 2008 Dec. PMID 18691253.
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