Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
RIN1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RIN1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q13671 |
| Other Accession | BC014417 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 1D11 |
| Calculated MW | 84099 Da |
| Gene ID | 9610 |
|---|---|
| Other Names | Ras and Rab interactor 1, Ras inhibitor JC99, Ras interaction/interference protein 1, RIN1 |
| Target/Specificity | RIN1 (AAH14417, 646 a.a. ~ 755 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RIN1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Cloning of a novel splicing variant of RIN1 and its expression in gastric and colon cancer. Fujioka M, et al. Oncol Res, 2009. PMID 19806790.Cell proliferation and epidermal growth factor signaling in non-small cell lung adenocarcinoma cell lines are dependent on Rin1. Tomshine JC, et al. J Biol Chem, 2009 Sep 25. PMID 19570984.Functional determinants of ras interference 1 mutants required for their inhbitory activity on endocytosis. Galvis A, et al. Exp Cell Res, 2009 Mar 10. PMID 19118546.Inhibition of early endosome fusion by Rab5-binding defective Ras interference 1 mutants. Galvis A, et al. Arch Biochem Biophys, 2009 Feb. PMID 19032933.RIN1 is a breast tumor suppressor gene. Milstein M, et al. Cancer Res, 2007 Dec 15. PMID 18089779.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
