RPL19 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RPL19.
|Application ||WB, IHC, IF, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||23466 Da|
|Other Names||60S ribosomal protein L19, RPL19|
|Target/Specificity||RPL19 (NP_000972, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||RPL19 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L19E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
1.Substitution p.A350V in Na(+)/Mg(2+) Exchanger SLC41A1, Potentially Associated with Parkinson's Disease, Is a Gain-of-Function Mutation.Kolisek M, Sponder G, Mastrototaro L, Smorodchenko A, Launay P, Vormann J, Schweigel-Rontgen MPLoS One. 2013 Aug 15;8(8):e71096. doi: 10.1371/journal.pone.0071096.2.Identification and expression of an autosomal paralogue of ribosomal protein S4, X-linked, in mice: Potential involvement of testis-specific ribosomal proteins in translation and spermatogenesis.Sugihara Y, Sadohara E, Yonezawa K, Kugo M, Oshima K, Matsuda T, Nadano D.Gene. 2013 May 25;521(1):91-9. doi: 10.1016/j.gene. 2013.02.0403.siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of Human Prostate Cancer.Bee A, Brewer D, Beesley C, Dodson A, Forootan S, Dickinson T, Gerard P, Lane B, Yao S, Cooper CS, Djamgoz MB, Gosden CM, Ke Y, Foster CS.PLoS One. 2011;6(7):e22672. Epub 2011 Jul 22.4.A conserved SET-domain methyltransferase, Set11, modifies ribosomal protein Rpl12 in fission yeast.Sadaie M, Shinmyozu K, Nakayama JI.J Biol Chem. 2008 Mar 14;283(11):7185-95. Epub 2008 Jan 14.
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