RSC1A1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RSC1A1.
|Application ||WB, IHC|
|Calculated MW||66790 Da|
|Other Names||Regulatory solute carrier protein family 1 member 1, Transporter regulator RS1, hRS1, RSC1A1|
|Target/Specificity||RSC1A1 (NP_006502, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||RSC1A1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Tripeptides of RS1 (RSC1A1) inhibit a monosaccharide-dependent exocytotic pathway of Na+-D-glucose cotransporter SGLT1 with high affinity. Vernaleken A, et al. J Biol Chem, 2007 Sep 28. PMID 17686765.Transporter regulator RS1 (RSC1A1) coats the trans-Golgi network and migrates into the nucleus. Kroiss M, et al. Am J Physiol Renal Physiol, 2006 Dec. PMID 16788147.RS1 (RSC1A1) regulates the exocytotic pathway of Na+-D-glucose cotransporter SGLT1. Veyhl M, et al. Am J Physiol Renal Physiol, 2006 Dec. PMID 16788146.Downregulation of the Na(+)- D-glucose cotransporter SGLT1 by protein RS1 (RSC1A1) is dependent on dynamin and protein kinase C. Veyhl M, et al. J Membr Biol, 2003 Nov 1. PMID 14724758.Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.
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