RXRG Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RXRG.
- CITATIONS: 1
|Application ||WB, E|
|Calculated MW||50871 Da|
|Other Names||Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3, Retinoid X receptor gamma, RXRG, NR2B3|
|Target/Specificity||RXRG (NP_008848, 1 a.a. ~ 75 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||RXRG Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described.
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? Rua?o G, et al. Pharmacogenomics, 2010 Jul. PMID 20602615.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Hou Z, et al. Proc Natl Acad Sci U S A, 2010 Feb 16. PMID 20133701.Epigenetic inactivation of retinoid X receptor genes in non-small cell lung cancer and the relationship with clinicopathologic features. Lee SM, et al. Cancer Genet Cytogenet, 2010 Feb. PMID 20113835.
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