S100A6 Antibody (monoclonal) (M10)
Mouse monoclonal antibody raised against a full length recombinant S100A6.
|Application ||WB, IHC, IF, E|
|Calculated MW||10180 Da|
|Other Names||Protein S100-A6, Calcyclin, Growth factor-inducible protein 2A9, MLN 4, Prolactin receptor-associated protein, PRA, S100 calcium-binding protein A6, S100A6, CACY|
|Target/Specificity||S100A6 (AAH01431, 1 a.a. ~ 90 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||S100A6 Antibody (monoclonal) (M10) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
1.Identification of novel molecular markers through transcriptomic analysis in human fetal and adult corneal endothelial cells.Chen Y, Huang K, Nakatsu MN, Xue Z, Deng SX, Fan G.Hum Mol Genet. 2013 Jan 8.2.S100A expression in normal corneal-limbal epithelial cells and ocular surface squamous cell carcinoma tissue.Li J, Riau AK, Setiawan M, Mehta JS, Ti SE, Tong L, Tan DT, Beuerman RW.Mol Vis. 2011;17:2263-71. Epub 2011 Aug 20.
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