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SEP11 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant SEPT11.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NVA2 |
| Other Accession | BC008083 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Lambda |
| Clone Names | 1E6 |
| Calculated MW | 49398 Da |
| Gene ID | 55752 |
|---|---|
| Other Names | Septin-11, SEPT11 |
| Target/Specificity | SEPT11 (AAH08083, 71 a.a. ~ 180 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SEP11 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al., 2004 [PubMed 15485874]).
References
LOH analysis of genes around D4S2964 identifies ARD1B as a prognostic predictor of hepatocellular carcinoma. Huang GL, et al. World J Gastroenterol, 2010 Apr 28. PMID 20419844.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Septin 11 restricts InlB-mediated invasion by Listeria. Mostowy S, et al. J Biol Chem, 2009 Apr 24. PMID 19234302.GTP binding is required for SEPT12 to form filaments and to interact with SEPT11. Ding X, et al. Mol Cells, 2008 May 31. PMID 18443421.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
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