SFN Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a full-length recombinant SFN.
|Application ||WB, IF, E|
|Calculated MW||27774 Da|
|Other Names||14-3-3 protein sigma, Epithelial cell marker protein 1, Stratifin, SFN, HME1|
|Target/Specificity||SFN (AAH00329.1, 1 a.a. ~ 248 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||SFN Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Hypermethylated 14-3-3-sigma and ESR1 gene promoters in serum as candidate biomarkers for the diagnosis and treatment efficacy of breast cancer metastasis. Zurita M, et al. BMC Cancer, 2010 May 20. PMID 20487521.The expression of seven 14-3-3 isoforms in human meningioma. Liu Y, et al. Brain Res, 2010 Jun 8. PMID 20388496.[Expression and clinical significance of 14-3-3 sigma and heat shock protein 27 in colorectal cancer] Pei HP, et al. Zhonghua Wei Chang Wai Ke Za Zhi, 2010 Mar. PMID 20336542.Reduced stratifin expression can serve as an independent prognostic factor for poor survival in patients with esophageal squamous cell carcinoma. Ren HZ, et al. Dig Dis Sci, 2010 Sep. PMID 20108042.Up-regulation of 14-3-3sigma (Stratifin) is associated with high-grade CIN and high-risk human papillomavirus (HPV) at baseline but does not predict outcomes of HR-HPV infections or incident CIN in the LAMS study. Syrj?nen S, et al. Am J Clin Pathol, 2010 Feb. PMID 20093232.
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