SGK2 Antibody (monoclonal) (M08)
Mouse monoclonal antibody raised against a partial recombinant SGK2.
|Application ||WB, IF, E|
|Calculated MW||47604 Da|
|Other Names||Serine/threonine-protein kinase Sgk2, Serum/glucocorticoid-regulated kinase 2, SGK2|
|Target/Specificity||SGK2 (AAH65511, 293 a.a. ~ 367 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||SGK2 Antibody (monoclonal) (M08) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Two alternate transcripts encoding two different isoforms have been described.
Sgk kinases and their role in epithelial transport. Loffing J, et al. Annu Rev Physiol, 2006. PMID 16460280.Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution. Cheng J, et al. Science, 2005 May 20. PMID 15790807.Regulation of cardiac shal-related potassium channel Kv 4.3 by serum- and glucocorticoid-inducible kinase isoforms in Xenopus oocytes. Baltaev R, et al. Pflugers Arch, 2005 Apr. PMID 15578212.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms. Embark HM, et al. Pflugers Arch, 2003 Feb. PMID 12634932.
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