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SH3BP2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant SH3BP2.

  • WB - SH3BP2 Antibody (monoclonal) (M01) AT3868a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.73 KDa) .
  • WB - SH3BP2 Antibody (monoclonal) (M01) AT3868a
    SH3BP2 monoclonal antibody (M01), clone 1E9 Western Blot analysis of SH3BP2 expression in A-431 ( (Cat # AT3868a )
  • IF - SH3BP2 Antibody (monoclonal) (M01) AT3868a
    Immunofluorescence of monoclonal antibody to SH3BP2 on A-431 cell. [antibody concentration 20 ug/ml]
  • E - SH3BP2 Antibody (monoclonal) (M01) AT3868a
    Detection limit for recombinant GST tagged SH3BP2 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P78314
Other Accession BC022996
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1E10
Calculated MW 62244 Da
Additional Information
Gene ID 6452
Other Names SH3 domain-binding protein 2, 3BP-2, SH3BP2, 3BP2
Target/Specificity SH3BP2 (AAH22996, 452 a.a. ~ 561 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSH3BP2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.


Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.NFATc1 and TNFalpha expression in giant cell lesions of the jaws. Amaral FR, et al. J Oral Pathol Med, 2010 Mar. PMID 20002873.Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFAT. Shukla U, et al. J Biol Chem, 2009 Dec 4. PMID 19833725.Novel mutations in the SH3BP2 gene associated with sporadic central giant cell lesions and cherubism. Carvalho VM, et al. Oral Dis, 2009 Jan. PMID 19017279.

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$ 315.00
Cat# AT3868a
(40 western blots)
Availability: 7-10 days
Bulk Size
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