SOX13 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant SOX13.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q9UN79 |
Other Accession | NM_005686 |
Reactivity | Human |
Host | mouse |
Clonality | Monoclonal |
Isotype | IgG1 Kappa |
Clone Names | 3E9 |
Calculated MW | 69228 Da |
Gene ID | 9580 |
---|---|
Other Names | Transcription factor SOX-13, Islet cell antigen 12, SRY (Sex determining region Y)-box 13, Type 1 diabetes autoantigen ICA12, SOX13 |
Target/Specificity | SOX13 (NP_005677, 25 a.a. ~ 138 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | SOX13 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12.
References
Interaction between Hhex and SOX13 modulates Wnt/TCF activity. Marfil V, et al. J Biol Chem, 2010 Feb 19. PMID 20028982.Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. Ehret GB, et al. Eur J Hum Genet, 2009 Dec. PMID 19536175.Functional proteomics mapping of a human signaling pathway. Colland F, et al. Genome Res, 2004 Jul. PMID 15231748.SOX13 autoantibodies are likely to be a supplementary marker for type 1 diabetes in Korea. Park Y, et al. Ann N Y Acad Sci, 2003 Nov. PMID 14679071.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
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