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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SPIRE1 Antibody (monoclonal) (M01)   

SPIRE1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant SPIRE1.

  • WB - SPIRE1 Antibody (monoclonal) (M01) AT4025a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.96 KDa) .
  • WB - SPIRE1 Antibody (monoclonal) (M01) AT4025a
    Western Blot analysis of SPIRE1 expression in transfected 293T cell line by SPIRE1 monoclonal antibody (M01), clone 4C5.

    Lane 1: SPIRE1 transfected lysate(15 KDa).
    Lane 2: Non-transfected lysate.
  • E - SPIRE1 Antibody (monoclonal) (M01) AT4025a
    Detection limit for recombinant GST tagged SPIRE1 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q08AE8
Other Accession NM_020148
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4C5
Calculated MW 85544 Da
Additional Information
Gene ID 56907
Other Names Protein spire homolog 1, Spir-1, SPIRE1 {ECO:0000312|EMBL:AAI252071}, KIAA1135, SPIR1
Target/Specificity SPIRE1 (NP_064533, 482 a.a. ~ 583 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSPIRE1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]).


1.Annexin A2-Dependent Polymerization of Actin Mediates Endosome Biogenesis.Morel E, Parton RG, Gruenberg J.Dev Cell. 2009 Mar;16(3):445-57.2.Actin S-Nitrosylation Inhibits Neutrophil {beta}2 Integrin Function.Thom SR, Bhopale VM, Mancini DJ, Milovanova TN.J Biol Chem. 2008 Apr 18;283(16):10822-34. Epub 2008 Feb 18.

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$ 315.00
Cat# AT4025a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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