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SUGT1 Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant SUGT1.

  • WB - SUGT1 Antibody (monoclonal) (M03) AT4103a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - SUGT1 Antibody (monoclonal) (M03) AT4103a
    SUGT1 monoclonal antibody (M03), clone 6G5 Western Blot analysis of SUGT1 expression in HeLa ( (Cat # AT4103a )
  • IF - SUGT1 Antibody (monoclonal) (M03) AT4103a
    Immunofluorescence of monoclonal antibody to SUGT1 on HeLa cell. [antibody concentration 10 ug/ml]
  • E - SUGT1 Antibody (monoclonal) (M03) AT4103a
    Detection limit for recombinant GST tagged SUGT1 is approximately 3ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y2Z0
Other Accession NM_006704
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG3 Kappa
Clone Names 6G5
Calculated MW 41024 Da
Additional Information
Gene ID 10910
Other Names Suppressor of G2 allele of SKP1 homolog, Protein 40-6-3, Sgt1, SUGT1
Target/Specificity SUGT1 (NP_006695, 151 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSUGT1 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants encoding different isoforms have been found for this gene.


Hsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites. Davies AE, et al. J Cell Biol, 2010 Apr 19. PMID 20404110.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Sgt1 dimerization is negatively regulated by protein kinase CK2-mediated phosphorylation at Ser361. Bansal PK, et al. J Biol Chem, 2009 Jul 10. PMID 19398558.Sgt1 has co-chaperone properties and is up-regulated by heat shock. Zabka M, et al. Biochem Biophys Res Commun, 2008 May 23. PMID 18358234.Hsp70 is a new target of Sgt1--an interaction modulated by S100A6. Spiechowicz M, et al. Biochem Biophys Res Commun, 2007 Jun 15. PMID 17466273.

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$ 315.00
Cat# AT4103a
(40 western blots)
Availability: 7-10 days
Bulk Size
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