SUOX Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant SUOX.
|Application ||WB, E|
|Calculated MW||60283 Da|
|Other Names||Sulfite oxidase, mitochondrial, SUOX|
|Target/Specificity||SUOX (AAH65193, 1 a.a. ~ 488 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||SUOX Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.
1.Demonstration of autoantibodies to recombinant human sulphite oxidase in patients with chronic liver disorders and analysis of their clinical relevance.Preuss B, Berg C, Altenberend F, Gregor M, Stevanovic S, Klein R.Clin Exp Immunol. 2007 Oct 15;150(2):312-321. Epub 2007 Aug 17.
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