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TAX1BP1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant TAX1BP1.

     
  • WB - TAX1BP1 Antibody (monoclonal) (M01) AT4156a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
    detail
  • WB - TAX1BP1 Antibody (monoclonal) (M01) AT4156a
    TAX1BP1 monoclonal antibody (M01), clone 2C3 Western Blot analysis of TAX1BP1 expression in A-431 ( (Cat # AT4156a )
    detail
  • WB - TAX1BP1 Antibody (monoclonal) (M01) AT4156a
    Western Blot analysis of TAX1BP1 expression in transfected 293T cell line by TAX1BP1 monoclonal antibody (M01), clone 2C3.

    Lane 1: TAX1BP1 transfected lysate(90.9 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • E - TAX1BP1 Antibody (monoclonal) (M01) AT4156a
    Detection limit for recombinant GST tagged TAX1BP1 is approximately 0.03ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q86VP1
Other Accession NM_006024
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2C3
Calculated MW 90877 Da
Additional Information
Gene ID 8887
Other Names Tax1-binding protein 1, TRAF6-binding protein, TAX1BP1, T6BP
Target/Specificity TAX1BP1 (NP_006015, 690 a.a. ~ 789 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsTAX1BP1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The HTLV-1 Tax protein transcriptionally activates the HTLV-1 promoter. Tax also binds to and stimulates the expression of cellular genes, including transcription factors and other proteins (Gachon et al., 1998 [PubMed 9733879]).

References

Analysis of the TAX1BP1 gene in head and neck cancer patients. Ruiz MT, et al. Braz J Otorhinolaryngol, 2010 Apr. PMID 20549079.TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases. Parvatiyar K, et al. J Biol Chem, 2010 May 14. PMID 20304918.Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes. Shembade N, et al. Science, 2010 Feb 26. PMID 20185725.The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling. Shembade N, et al. EMBO J, 2009 Mar 4. PMID 19131965.Genetic variation in the nuclear factor kappaB pathway in relation to susceptibility to rheumatoid arthritis. Dieguez-Gonzalez R, et al. Ann Rheum Dis, 2009 Apr. PMID 18434448.

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$ 350.00
Cat# AT4156a
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Availability: 7-10 days
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