TNFRSF8 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant TNFRSF8.
|Calculated MW||63747 Da|
|Other Names||Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, CD30, D1S166E|
|Target/Specificity||TNFRSF8 (NP_001234, 21 a.a. ~ 133 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||TNFRSF8 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Serial soluble CD30 measurements as a predictor of kidney graft outcome. Halim MA, et al. Transplant Proc, 2010 Apr. PMID 20430176.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Posttransplant soluble CD30 as a predictor of acute renal allograft rejection. Kamali K, et al. Exp Clin Transplant, 2009 Dec. PMID 20353374.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Altered expression of the lymphocyte activation antigen CD30 in active celiac disease. Periolo N, et al. Autoimmunity, 2010 Jun. PMID 20166880.
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