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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   UBR1 Antibody (monoclonal) (M01)   

UBR1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant UBR1.

  • WB - UBR1 Antibody (monoclonal) (M01) AT4450a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
  • WB - UBR1 Antibody (monoclonal) (M01) AT4450a
    UBR1 monoclonal antibody (M01), clone 2F5 Western Blot analysis of UBR1 expression in Hela S3 NE ( (Cat # AT4450a )
  • E - UBR1 Antibody (monoclonal) (M01) AT4450a
    Detection limit for recombinant GST tagged UBR1 is approximately 0.03ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IWV7
Other Accession NM_17491
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2F5
Calculated MW 200211 Da
Additional Information
Gene ID 197131
Other Names E3 ubiquitin-protein ligase UBR1, 632-, N-recognin-1, Ubiquitin-protein ligase E3-alpha-1, Ubiquitin-protein ligase E3-alpha-I, UBR1
Target/Specificity UBR1 (NP_777576, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsUBR1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.


1.Roles of STAT3/SOCS3 pathway in regulation of the visual function and ubiquitin proteasome-dependent degradation of Rhodopsin during retinal inflammation.Ozawa Y, Nakao K, Kurihara T, Shimazaki T, Shimmura S, Ishida S, Yoshimura A, Tsubota K, Okano H.J Biol Chem. 2008 Sep 5;283(36):24561-70. Epub 2008 Jul 9.

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$ 315.00
Cat# AT4450a
(40 western blots)
Availability: 7-10 days
Bulk Size
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