UGT2B10 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant UGT2B10.
|Application ||WB, E|
|Calculated MW||60774 Da|
|Other Names||UDP-glucuronosyltransferase 2B10, UDPGT 2B10, UGT2B10|
|Target/Specificity||UGT2B10 (NP_001066, 62 a.a. ~ 159 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||UGT2B10 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
UGT2B10 genotype influences nicotine glucuronidation, oxidation, and consumption. Berg JZ, et al. Cancer Epidemiol Biomarkers Prev, 2010 Jun. PMID 20501767.Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines. Chen G, et al. Pharmacogenet Genomics, 2008 Mar. PMID 18300939.Glucuronidation of nicotine and cotinine by UGT2B10: loss of function by the UGT2B10 Codon 67 (Asp>Tyr) polymorphism. Chen G, et al. Cancer Res, 2007 Oct 1. PMID 17909004.Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10. Kaivosaari S, et al. Mol Pharmacol, 2007 Sep. PMID 17576790.Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. Liu T, et al. J Proteome Res, 2005 Nov-Dec. PMID 16335952.
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