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VIL2 Antibody (monoclonal) (M04)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT4512a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
VIL2 Antibody (monoclonal) (M04) - Product info | |
| Application | WB
|
| Primary Accession | P15311 |
| Reactivity | Human |
| Isotype | IgG2b Kappa |
| Clone Names | 100000000000 |
| Calculated MW | 69413 Da |
VIL2 Antibody (monoclonal) (M04) - Additional info | |
| Gene ID 7430 | |
| Other Names CVIL, CVL, DKFZp762H157, MGC1584villin 2 (ezrin) | |
| Target/Specificity VIL2 (AAH13903, 1 a.a. ~ 587 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions VIL2 Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures. | |
VIL2 Antibody (monoclonal) (M04) - Related products
AP5845a: EZRIN Antibody (N-term)
VIL2 Antibody (monoclonal) (M04) - Application data
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VIL2 monoclonal antibody (M04), clone 1E11. Western Blot analysis of VIL2 expression in HepG2 ( Cat # L019V1 ).
VIL2 Antibody (monoclonal) (M04) - Research Areas
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BACKGROUND
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
REFERENCES
Ezrin immunoreactivity in renal cell carcinomas. Tuna B, et al. Anal Quant Cytol Histol, 2009 Oct. PMID 20701102.Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility hot-spot. Johnatty SE, et al. PLoS Genet, 2010 Jul 8. PMID 20628624.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Immunoexpression of Ezrin and CD44 in patients with osteosarcoma. Boldrini E, et al. J Pediatr Hematol Oncol, 2010 Aug. PMID 20562647.Ezrin immunohistochemical expression in chondrosarcomas, osteosarcomas and Ewing sarcoma family of tumors. Machado I, et al. Virchows Arch, 2010 Jul. PMID 20552365.
