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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   VPS18 Antibody (monoclonal) (M02)   

VPS18 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant VPS18.

     
  • WB - VPS18 Antibody (monoclonal) (M02) AT4520a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) .
  • WB - VPS18 Antibody (monoclonal) (M02) AT4520a
    VPS18 monoclonal antibody (M02), clone 2G10. Western Blot analysis of VPS18 expression in Raw 264.7.
  • E - VPS18 Antibody (monoclonal) (M02) AT4520a
    Detection limit for recombinant GST tagged VPS18 is approximately 3ng/ml as a capture antibody.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9P253
Other Accession NM_020857
Reactivity Human, Mouse
Host mouse
Clonality Monoclonal
Isotype IgG3 Kappa
Clone Names 2G10
Calculated MW 110186 Da
Additional Information
Gene ID 57617
Other Names Vacuolar protein sorting-associated protein 18 homolog, hVPS18, VPS18, KIAA1475
Target/Specificity VPS18 (NP_065908, 3 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsVPS18 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Background

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.

References

1.The cellular factors Vps18 and Mon2 are required for efficient production of infectious HIV-1 particles.Tomita Y, Noda T, Fujii K, Watanabe T, Morikawa Y, Kawaoka Y.J Virol. 2011 Mar 30. [Epub ahead of print]

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$ 315.00
Cat# AT4520a
Size:
Quantity:
(40 western blots)
Availability: 7-10 days
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