VPS18 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant VPS18.
|Application ||WB, E|
|Calculated MW||110186 Da|
|Other Names||Vacuolar protein sorting-associated protein 18 homolog, hVPS18, VPS18, KIAA1475|
|Target/Specificity||VPS18 (NP_065908, 3 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||VPS18 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
1.The cellular factors Vps18 and Mon2 are required for efficient production of infectious HIV-1 particles.Tomita Y, Noda T, Fujii K, Watanabe T, Morikawa Y, Kawaoka Y.J Virol. 2011 Mar 30. [Epub ahead of print]
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