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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   WASF2 Antibody (monoclonal) (M02)   

WASF2 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant WASF2.

  • WB - WASF2 Antibody (monoclonal) (M02) AT4526a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • WB - WASF2 Antibody (monoclonal) (M02) AT4526a
    WASF2 monoclonal antibody (M02), clone 8E7 Western Blot analysis of WASF2 expression in HeLa ( (Cat # AT4526a )
  • E - WASF2 Antibody (monoclonal) (M02) AT4526a
    Detection limit for recombinant GST tagged WASF2 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y6W5
Other Accession NM_006990
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 8E8
Calculated MW 54284 Da
Additional Information
Gene ID 10163
Other Names Wiskott-Aldrich syndrome protein family member 2, WASP family protein member 2, Protein WAVE-2, Verprolin homology domain-containing protein 2, WASF2, WAVE2
Target/Specificity WASF2 (NP_008921, 73 a.a. ~ 172 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsWASF2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X.


Directional control of WAVE2 membrane targeting by EB1 and phosphatidylinositol 3,4,5-triphosphate. Takahashi K, et al. Cell Signal, 2010 Mar. PMID 19925864.Activation of the WAVE complex by coincident signals controls actin assembly. Lebensohn AM, et al. Mol Cell, 2009 Nov 13. PMID 19917258.Metastatic potential of lung squamous cell carcinoma associated with HSPC300 through its interaction with WAVE2. Cai X, et al. Lung Cancer, 2009 Sep. PMID 19576655.BetaPIX and GIT1 regulate HGF-induced lamellipodia formation and WAVE2 transport. Morimura S, et al. Biochem Biophys Res Commun, 2009 May 8. PMID 19303398.Membrane transport of WAVE2 and lamellipodia formation require Pak1 that mediates phosphorylation and recruitment of stathmin/Op18 to Pak1-WAVE2-kinesin complex. Takahashi K, et al. Cell Signal, 2009 May. PMID 19162178.

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$ 315.00
Cat# AT4526a
(40 western blots)
Availability: 7-10 days
Bulk Size
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