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PE Anti-Human CD38 (HIT2) Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC |
|---|---|
| Isotype | Mouse IgG1, kappa |
| Concentration | 5 uL (0.5 ug)/test |
| Reactivity | Human |
| Formulation | 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2 |
| Host | Mouse |
| Format | PE |
|---|---|
| Storage Conditions | 2-8°C protected from light |
Provided below are standard protocols that you may find useful for product applications.
Background
The HIT2 antibody is specific for human CD38, a 45 kD type II transmembrane glycoprotein expressed on thymocytes, activated T and B cells, and monocytes as well as other non-hematopoietic cells. CD38 is an ectoenzyme that functions to catalyze the synthesis and hydrolysis of cyclic ADP-ribose and is involved in cell signaling, regulating cell adhesion, and activation. Additionally, CD38 has been shown to be a prognostic marker for some leukemias and other diseases.
References
Dianzani U, and Malavasi F. 1995. Crit. Rev. Immunol. 15(2):167-200.
Mehta K, Shahid U, and Malavasi F. Oct. 1996. FASEB J. 10(12):1408-1417.
Ferrero E, and Malavas F. Feb. 1999. J. Jeukoc. Biol. 65(2):151-161.
Matrai Z. Feb. 2005. Hematology. 10(1):39-46.
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