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PMM2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - PMM2 Antibody (C-term) AW5044-U400
    Western blot analysis of lysates from Hela, HepG2, K562, MCF-7 cell line (from left to right), using PMM2 Antibody (C-term)(Cat. #AW5044). AW5044 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15305
Other Accession Q9Z2M7, Q60HD6, Q3SZJ9, NP_000294.1
Reactivity Human
Predicted Mouse, Monkey, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 28082 Da
Additional Information
Gene ID 5373
Antigen Region 198-226 aa
Other Names PMM2; Phosphomannomutase 2
Dilution WB~~1:1000
Target/Specificity This PMM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human PMM2.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPMM2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PMM2
Function Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Cellular Location Cytoplasm.
Citations (0)

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The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. [provided by RefSeq].


Vega, A.I., et al. Hum. Mutat. 30(5):795-803(2009)
Coman, D., et al. Am. J. Med. Genet. A 146(3):389-392(2008)
Vermeer, S., et al. J. Neurol. 254(10):1356-1358(2007)
Coman, D., et al. J Clin Neurosci 14(7):668-672(2007)
Schollen, E., et al. Mol. Genet. Metab. 90(4):408-413(2007)

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$ 325.00
$ 110.00
Cat# AW5044-U400
(40 western blots)
Availability: In Stock
Bulk Size
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