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DANREs1pr1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - DANREs1pr1 Antibody (C-term) Azb10039a
    DANREs1pr1 Antibody (C-term) (Cat. #Azb10039a) western blot analysis in zebra fish brain tissue lysates (35ug/lane).This demonstrates the DANREs1pr1 antibody detected the DANREs1pr1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9DDK4
Reactivity Zebrafish
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 40601 Da
Antigen Region 311-335 aa
Additional Information
Gene ID 64617
Other Names Sphingosine 1-phosphate receptor 1, S1P receptor 1, S1P1, Sphingosine 1-phosphate receptor Edg-1, S1P receptor Edg-1, s1pr1, edg1
Target/Specificity This DANREs1pr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-335 amino acids from the C-terminal region of DANREs1pr1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDANREs1pr1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name s1pr1
Synonyms edg1
Function G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Seems to be coupled to the G(i) subclass of heteromeric G proteins.


Im D.-S., et al. Biochem. Biophys. Res. Commun. 279:139-143(2000).

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Cat# Azb10039a
(40 western blots)
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