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SLC43A2 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8N370 |
|---|---|
| Other Accession | NP_689559.1 |
| Clone Names | 100107120 |
| Gene ID | 124935 |
|---|---|
| Other Names | Large neutral amino acids transporter small subunit 4, L-type amino acid transporter 4, Solute carrier family 43 member 2, SLC43A2, LAT4 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC43A2 (HGNC:23087) |
|---|---|
| Synonyms | LAT4 |
| Function | Uniporter that mediates the transport of the stereospecific L-phenylalanine, L-methionine and L-branched-chain amino acids, between the extracellular space and the cytoplasm and may control the transepithelial (re)absorption of neutral amino acid in kidney and small intestine (PubMed:30379325, PubMed:15659399). The transport activity is mediated through facilitated diffusion and is sodium ions-, chloride ions- and pH-independent (PubMed:15659399). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Basolateral cell membrane {ECO:0000250|UniProtKB:Q8CGA3}. Note=Located at the basolateral membrane in the small intestine enterocytes, kidney proximal tubule, thick ascending limb and, to a minor extent, of distal convoluted tubule epithelial cells. {ECO:0000250|UniProtKB:Q8CGA3} |
| Tissue Location | Detected in several tissues with higher expression in placenta, kidney and peripheral blood leukocytes (PubMed:15659399) In the kidney, is detected in epithelial cells of the distal tubule and collecting duct (PubMed:15659399). In the intestine, is expressed mainly in crypt cells of the intestinal microvilli and epithelial cells in the base of the villus (PubMed:15659399) |
Research Areas
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Application Protocols
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$ 277.78
Cat# BP10062c
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