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C12orf48 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NWS1 |
|---|---|
| Other Accession | NP_060385.3 |
| Clone Names | 100107254 |
| Gene ID | 55010 |
|---|---|
| Other Names | PCNA-interacting partner, PARI, PARP-1 binding protein, PARP1-binding protein, PARPBP, PARPBP, C12orf48, PARI |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PARPBP |
|---|---|
| Synonyms | C12orf48, PARI |
| Function | Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. Binds single-strand DNA and poly(A) homopolymers. Positively regulate the poly(ADP-ribosyl)ation activity of PARP1; however such function may be indirect. |
| Cellular Location | Cytoplasm. Nucleus Note=Localizes to chromatin in response to S phase arrest but not in mitosis. Targeted to chromatin via its interaction with PCNA |
| Tissue Location | Restricted to testis. Overexpressed in multiple cancer cells. |
Research Areas
Citations (0)
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$ 277.78
Cat# BP10083b
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