|Other Names||A disintegrin and metalloproteinase with thrombospondin motifs 17, ADAM-TS 17, ADAM-TS17, ADAMTS-17, 3424-, ADAMTS17|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Isoform 1 and isoform 2 are expressed at high levels in the lung, brain, whole eye and retina. Isoform 1 shows a weaker expression in the heart, kidney and skeletal muscle Isoform 2 shows a weaker expression in the kidney, bone marrow and skeletal muscle. Isoform 1 and isoform 2 are expressed at high levels in the fetal heart, kidney, and whole eye, whereas a weak expression is seen in the fetal liver|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the ADAMTS (a disintegrinand metalloproteinase with thrombospondin motifs) protein family.ADAMTS family members share several distinct protein modules,including a propeptide region, a metalloproteinase domain, adisintegrin-like domain, and a thrombospondin type 1 (TS) motif.Individual members of this family differ in the number ofC-terminal TS motifs, and some have unique C-terminal domains. Theprotein encoded by this gene has a high sequence similarity to theprotein encoded by ADAMTS19, another family member. The function ofthis protein has not been determined.
Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010)Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :Morales, J., et al. Am. J. Hum. Genet. 85(5):558-568(2009)Sovio, U., et al. PLoS Genet. 5 (3), E1000409 (2009) :Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.