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AHSG Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P02765 |
|---|---|
| Other Accession | NP_001613.2 |
| Clone Names | 80902059 |
| Gene ID | 197 |
|---|---|
| Other Names | Alpha-2-HS-glycoprotein, Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A, Alpha-2-HS-glycoprotein chain A, Alpha-2-HS-glycoprotein chain B, AHSG, FETUA |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | AHSG |
|---|---|
| Synonyms | FETUA |
| Function | Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. |
| Cellular Location | Secreted. |
| Tissue Location | Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins |
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Provided below are standard protocols that you may find useful for product applications.
Background
Alpha2-HS glycoprotein (AHSG), a glycoprotein present inthe serum, is synthesized by hepatocytes. The AHSG moleculeconsists of two polypeptide chains, which are both cleaved from aproprotein encoded from a single mRNA. It is involved in severalfunctions, such as endocytosis, brain development and the formationof bone tissue. The protein is commonly present in the corticalplate of the immature cerebral cortex and bone marrow hemopoieticmatrix, and it has therefore been postulated that it participatesin the development of the tissues. However, its exact significanceis still obscure.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Verduijn, M., et al. Nephrol. Dial. Transplant. (2010) In press :Wang, Y., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27(3):310-315(2010)Voigt, M., et al. Histopathology 56(6):775-788(2010)Kusnierz-Cabala, B., et al. Clin. Lab. 56 (5-6), 191-195 (2010) :
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