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AGTR1 Antibody (Center) Blocking peptideSynthetic peptide
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| BP10119b | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
AGTR1 Antibody (Center) Blocking peptide - Product info | |
| Primary Accession | P30556 |
| Other Accession | NP_114438.1, NP_114038.1, NP_004826.2, NP_033611.1, NP_000676.1 |
| Clone Names | 80924047 |
| Calculated MW | 41061 Da |
AGTR1 Antibody (Center) Blocking peptide - Additional info | |
| Gene ID 185 | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
AGTR1 Antibody (Center) Blocking peptide - Protein Information | |
| Name AGTR1 | |
| Synonyms AGTR1A, AGTR1B, AT2R1, AT2R1B | |
| Function Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system | |
| Cellular Location Cell membrane; Multi-pass membrane protein. | |
| Tissue Location Liver, lung, adrenal and adrenocortical adenomas | |
AGTR1 Antibody (Center) Blocking peptide - Related products
AP10119b: AGTR1 Antibody (Center)
AGTR1 Antibody (Center) Blocking peptide - Research Areas
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BACKGROUND
Angiotensin II is a potent vasopressor hormone and aprimary regulator of aldosterone secretion. It is an importanteffector controlling blood pressure and volume in thecardiovascular system. It acts through at least two types ofreceptors. This gene encodes the type 1 receptor which is thoughtto mediate the major cardiovascular effects of angiotensin II. Thisgene may play a role in the generation of reperfusion arrhythmiasfollowing restoration of blood flow to ischemic or infarctedmyocardium. It was previously thought that a related gene, denotedas AGTR1B, existed; however, it is now believed that there is onlyone type 1 receptor gene in humans. At least five transcriptvariants have been described for this gene. Additional variantshave been described but their full-length nature has not beendetermined. The entire coding sequence is contained in the terminalexon and is present in all transcript variants. [provided byRefSeq].
REFERENCES
Xu, M., et al. Atherosclerosis 213(1):191-199(2010)Niu, W., et al. Hypertens. Res. 33(11):1137-1143(2010)Procopciuc, L.M., et al. Eur. J. Intern. Med. 21(5):414-418(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Schuur, M., et al. J. Neurol. Neurosurg. Psychiatr. (2010) In press :
