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ABCC10 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q5T3U5
Other Accession NP_258261.2
Clone Names 90819012
Peptide ID 90819012
Additional Information
Gene ID 89845
Other Names Multidrug resistance-associated protein 7, ATP-binding cassette sub-family C member 10, ABCC10, MRP7, SIMRP7
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ABCC10
Synonyms MRP7, SIMRP7
Function ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.
Cellular Location Cell membrane; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:12566991, ECO:0000269|PubMed:15256465}
Tissue Location Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed.
Research Areas
Citations (0)

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Background

The protein encoded by this gene is a member of thesuperfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- andintra-cellular membranes. ABC genes are divided into seven distinctsubfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). ThisABC full-transporter is a member of the MRP subfamily which isinvolved in multi-drug resistance. Multiple transcript variantsencoding different isoforms have been found for this gene.

References

Kuang, Y.H., et al. Biochem. Pharmacol. 79(2):154-161(2010)Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)Zhou, Y., et al. Biochem. Pharmacol. 77(6):993-1001(2009)Hopper-Borge, E., et al. Cancer Res. 69(1):178-184(2009)Shen, T., et al. PLoS ONE 4 (10), E7520 (2009) :

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$ 80.00
Cat# BP10143c
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