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DUSP26 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BV47 |
|---|---|
| Other Accession | NP_076930.1 |
| Clone Names | 90904133 |
| Gene ID | 78986 |
|---|---|
| Other Names | Dual specificity protein phosphatase 26, Dual specificity phosphatase SKRP3, Low-molecular-mass dual-specificity phosphatase 4, DSP-4, LDP-4, Mitogen-activated protein kinase phosphatase 8, MAP kinase phosphatase 8, MKP-8, Novel amplified gene in thyroid anaplastic cancer, DUSP26, DUSP24, LDP4, MKP8, NATA1, SKRP3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DUSP26 |
|---|---|
| Synonyms | DUSP24, LDP4, MKP8, NATA1, SKRP3 |
| Function | Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). |
| Cellular Location | Cytoplasm. Nucleus. Golgi apparatus. |
| Tissue Location | Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Shang, X., et al. Oncogene 29(35):4938-4946(2010)Patterson, K.I., et al. Biochim. Biophys. Acta 1803(9):1003-1012(2010)Tanuma, N., et al. Oncogene 28(5):752-761(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)Yu, W., et al. Oncogene 26(8):1178-1187(2007)
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