|Other Names||Betaine--homocysteine S-methyltransferase 1, BHMT|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.|
|Tissue Location||Found exclusively in liver and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a cytosolic enzyme that catalyzes theconversion of betaine and homocysteine to dimethylglycine andmethionine, respectively. Defects in this gene could lead tohyperhomocyst(e)inemia, but such a defect has not yet beenobserved.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Giusti, B., et al. Thromb. Haemost. 104(2):231-242(2010)Hobbs, C.A., et al. Obstet Gynecol 116 (2 PT 1), 316-322 (2010) :Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
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