GGTLC2 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q14390 |
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Other Accession | NP_954578.2 |
Clone Names | 91013011 |
Gene ID | 91227 |
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Other Names | Gamma-glutamyltransferase light chain 2, Gamma-glutamyltransferase-like protein 4, GGTLC2, GGTL4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GGTLC2 |
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Synonyms | GGTL4 |
Tissue Location | Placenta and sigmoid tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Gamma-glutamyltransferase-1 (GGT1; MIM 612346) is amembrane-bound extracellular enzyme that cleaves gamma-glutamylpeptide bonds in glutathione and other peptides and transfers thegamma-glutamyl moiety to acceptors. Autocatalytic cleavage of theGGT1 precursor polypeptide produces a heavy chain and a light chainthat associate with each other to form the functional enzyme. Lightchain-only GGTs, such as GGTLC2, contain a region corresponding tothe GGT1 light chain, but they lack the membrane-anchoring heavychain region (Heisterkamp et al., 2008 [PubMed 18357469]).[suppliedby OMIM].
References
Heisterkamp, N., et al. Hum. Genet. 123(4):321-332(2008)Dunham, I., et al. Nature 402(6761):489-495(1999)Kawasaki, K., et al. Genome Res. 7(3):250-261(1997)Leh, H., et al. FEBS Lett. 394(3):258-262(1996)Wetmore, L.A., et al. Proc. Natl. Acad. Sci. U.S.A. 90(16):7461-7465(1993)
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