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GLRA2 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P23416
Other Accession NP_001165413.1, NP_001112358.1, NP_002054.1, NP_001112357.1
Clone Names 91013022
Peptide ID 91013022
Additional Information
Gene ID 2742
Other Names Glycine receptor subunit alpha-2, GLRA2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GLRA2
Function Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:2155780, PubMed:15302677, PubMed:16144831, PubMed:23895467, PubMed:25445488). Channel opening is also triggered by taurine and beta-alanine (PubMed:15302677). Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488). Plays a role in cellular responses to ethanol (PubMed:23895467).
Cellular Location Cell junction, synapse, postsynaptic cell membrane {ECO:0000250|UniProtKB:Q7TNC8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P23415}. Cell junction, synapse {ECO:0000250|UniProtKB:Q7TNC8}. Cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:P23415}. Cell projection {ECO:0000250|UniProtKB:Q7TNC8}
Research Areas
Citations (0)

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The glycine receptor consists of two subunits, alpha andbeta, and acts as a pentamer. The protein encoded by this gene isan alpha subunit and can bind strychnine. Several transcriptvariants encoding different isoforms have been found for this gene.


Hong, C.W., et al. J. Immunol. 184(8):4401-4413(2010)Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :Lamesch, P., et al. Genomics 89(3):307-315(2007)Miller, P.S., et al. J. Biol. Chem. 280(45):37877-37884(2005)

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$ 80.00
Cat# BP10217c
Availability: In Stock
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