GTF3C6 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q969F1 |
---|---|
Other Accession | NP_612417.1 |
Clone Names | 91013086 |
Gene ID | 112495 |
---|---|
Other Names | General transcription factor 3C polypeptide 6, Transcription factor IIIC 35 kDa subunit, TFIIIC 35 kDa subunit, TFIIIC35, Transcription factor IIIC subunit 6, GTF3C6, C6orf51 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GTF3C6 |
---|---|
Synonyms | C6orf51 |
Function | Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters. |
Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
RNA polymerases are unable to initiate RNA synthesis inthe absence of additional proteins called general transcriptionfactors (GTFs). GTFs assemble in a complex on the DNA promoter andrecruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1,MIM 603246) are essential for RNA polymerase III to make a numberof small nuclear and cytoplasmic RNAs, including 5S RNA (MIM180420), tRNA, and adenovirus-associated (VA) RNA of both cellularand viral origin.
References
Dumay-Odelot, H., et al. J. Biol. Chem. 282(23):17179-17189(2007)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.