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KLDC3 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9BQ90
Other Accession NP_476502.1
Clone Names 91109277
Peptide ID 91109277
Additional Information
Other Names Kelch domain-containing protein 3, Protein Peas, Testis intracellular mediator protein, KLHDC3, PEAS
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PEAS
Function May be involved in meiotic recombination process.
Cellular Location Cytoplasm. Note=Also found in meiotic chromatin. EMBL; AB055925; BAB63257.1; -; mRNA EMBL; AK290384; BAF83073.1; -; mRNA EMBL; AL136304; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; CH471081; EAX04136.1; -; Genomic_DNA EMBL; BC000295; AAH00295.1; -; mRNA EMBL; BC001789; AAH01789.1; -; mRNA EMBL; BC001793; AAH01793.1; -; mRNA EMBL; BC007296; AAH07296.1; -; mRNA EMBL; BC021546; AAH21546.1; -; mRNA CCDS; CCDS4880.1; - RefSeq; NP_476502.1; NM_057161.3 UniGene; Hs.412468; - ProteinModelPortal; Q9BQ90; - BioGrid; 125478; 55 IntAct; Q9BQ90; 4 STRING; 9606.ENSP00000313995; - iPTMnet; Q9BQ90; - PhosphoSitePlus; Q9BQ90; - BioMuta; KLHDC3; - DMDM; 74752233; - EPD; Q9BQ90; - MaxQB; Q9BQ90; - PaxDb; Q9BQ90; - PeptideAtlas; Q9BQ90; - PRIDE; Q9BQ90; - ProteomicsDB; 78644; - DNASU; 116138; - Ensembl; ENST00000326974; ENSP00000313995; ENSG00000124702 GeneID; 116138; - KEGG; hsa:116138; - UCSC; uc003otl.4; human CTD; 116138; - EuPathDB; HostDB:ENSG00000124702.17; - GeneCards; KLHDC3; - HGNC; HGNC:20704; KLHDC3 HPA; HPA030131; - HPA; HPA030132; - HPA; HPA030133; - HPA; HPA030134; - MIM; 611248; gene neXtProt; NX_Q9BQ90; - OpenTargets; ENSG00000124702; - PharmGKB; PA134892782; - eggNOG; KOG0379; Eukaryota eggNOG; ENOG410Y5WM; LUCA GeneTree; ENSGT00760000119086; - HOGENOM; HOG000276538; - HOVERGEN; HBG071311; - InParanoid; Q9BQ90; - PhylomeDB; Q9BQ90; - TreeFam; TF354289; - Reactome; R-HSA-381038; XBP1(S) activates chaperone genes ChiTaRS; KLHDC3; human GeneWiki; KLHDC3; - GenomeRNAi; 116138; - PRO; PR:Q9BQ90; - Proteomes; UP000005640; Chromosome 6 Bgee; ENSG00000124702; - CleanEx; HS_KLHDC3; - ExpressionAtlas; Q9BQ90; baseline and differential Genevisible; Q9BQ90; HS GO; GO:0005737; C:cytoplasm; IDA:UniProtKB GO; GO:0005829; C:cytosol; TAS:Reactome GO; GO:0000790; C:nuclear chromatin; IDA:UniProtKB GO; GO:0005654; C:nucleoplasm; IDA:HPA GO; GO:0003682; F:chromatin binding; IDA:UniProtKB GO; GO:0036498; P:IRE1-mediated unfolded protein response; TAS:Reactome GO; GO:0007131; P:reciprocal meiotic recombination; NAS:UniProtKB Gene3D;; -; 2 InterPro; IPR015915; Kelch-typ_b-propeller InterPro; IPR011498; Kelch_2 Pfam; PF07646; Kelch_2; 2 SUPFAM; SSF117281; SSF117281; 2 2: Evidence at transcript level; Complete proteome; Cytoplasm; Kelch repeat; Meiosis; Reference proteome; Repeat CHAIN 1 382 Kelch domain-containing protein 3 /FTId=PRO_0000228995 REPEAT 25 77 Kelch 1 REPEAT 88 138 Kelch 2 REPEAT 139 189 Kelch 3 REPEAT 191 249 Kelch 4 REPEAT 251 301 Kelch 5 SEQUENCE 382 AA; 43088 MW; 49A3AB24BE7FFAFC CRC64; MLRWTVHLEG GPRRVNHAAV AVGHRVYSFG GYCSGEDYET LRQIDVHIFN AVSLRWTKLP PVKSAIRGQA PVVPYMRYGH STVLIDDTVL LWGGRNDTEG ACNVLYAFDV NTHKWFTPRV SGTVPGARDG HSACVLGKIM YIFGGYEQQA DCFSNDIHKL DTSTMTWTLI CTKGSPARWR DFHSATMLGS HMYVFGGRAD RFGPFHSNNE IYCNRIRVFD TRTEAWLDCP PTPVLPEGRR SHSAFGYNGE LYIFGGYNAR LNRHFHDLWK FNPVSFTWKK IEPKGKGPCP RRRQCCCIVG DKIVLFGGTS PSPEEGLGDE FDLIDHSDLH ILDFSPSLKT LCKLAVIQYN LDQSCLPHDI RWELNAMTTN SNISRPIVSS HG
Research Areas
Citations (0)

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The protein encoded by this gene contains six repeatedkelch motifs that are structurally similar to recombinationactivating gene 2 (RAG2), a protein involved in the activation ofthe V(D)J recombination. In mouse, this gene is found to expressspecifically in testis. Its expression in pachytene spermatocytesis localized to cytoplasma and meiotic chromatin, which suggeststhat this gene may be involved in meiotic recombination. [providedby RefSeq].


Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Mungall, A.J., et al. Nature 425(6960):805-811(2003)Ohinata, Y., et al. DNA Res. 10(2):79-84(2003)

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$ 80.00
Cat# BP10224b
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