|Other Names||Kelch domain-containing protein 3, Protein Peas, Testis intracellular mediator protein, KLHDC3, PEAS|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in meiotic recombination process.|
|Cellular Location||Cytoplasm. Note=Also found in meiotic chromatin.|
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The protein encoded by this gene contains six repeatedkelch motifs that are structurally similar to recombinationactivating gene 2 (RAG2), a protein involved in the activation ofthe V(D)J recombination. In mouse, this gene is found to expressspecifically in testis. Its expression in pachytene spermatocytesis localized to cytoplasma and meiotic chromatin, which suggeststhat this gene may be involved in meiotic recombination. [providedby RefSeq].
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Mungall, A.J., et al. Nature 425(6960):805-811(2003)Ohinata, Y., et al. DNA Res. 10(2):79-84(2003)
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