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DSN1 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H410 |
|---|---|
| Other Accession | NP_001138788.1, NP_001138787.1, NP_079194.3 |
| Clone Names | 90921138 |
| Gene ID | 79980 |
|---|---|
| Other Names | Kinetochore-associated protein DSN1 homolog, DSN1, C20orf172, MIS13 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DSN1 |
|---|---|
| Synonyms | C20orf172, MIS13 |
| Function | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. |
| Cellular Location | Nucleus. Chromosome, centromere, kinetochore Note=Associated with the kinetochore. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a kinetochore protein that functions aspart of the minichromosome instability-12 centromere complex. Theencoded protein is required for proper kinetochore assembly andprogression through the cell cycle. Alternative splicing results inmultiple transcript variants.
References
Yang, Y., et al. J. Biol. Chem. 283(39):26726-26736(2008)Cheeseman, I.M., et al. Nat. Rev. Mol. Cell Biol. 9(1):33-46(2008)Kiyomitsu, T., et al. Dev. Cell 13(5):663-676(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Kline, S.L., et al. J. Cell Biol. 173(1):9-17(2006)
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