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RPS6 (Ser240/244) Antibody Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P62753
Other Accession NP_001001.2
Clone Names 91223004
Peptide ID 91223004
Additional Information
Gene ID 6194
Other Names 40S ribosomal protein S6, Phosphoprotein NP33, RPS6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RPS6
Function May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.
Research Areas
Citations (0)

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Background

Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a cytoplasmicribosomal protein that is a component of the 40S subunit. Theprotein belongs to the S6E family of ribosomal proteins. It is themajor substrate of protein kinases in the ribosome, with subsets offive C-terminal serine residues phosphorylated by different proteinkinases. Phosphorylation is induced by a wide range of stimuli,including growth factors, tumor-promoting agents, and mitogens.Dephosphorylation occurs at growth arrest. The protein maycontribute to the control of cell growth and proliferation throughthe selective translation of particular classes of mRNA. As istypical for genes encoding ribosomal proteins, there are multipleprocessed pseudogenes of this gene dispersed through the genome.

References

Maggi, L.B. Jr., et al. Mol. Cell. Biol. 28(23):7050-7065(2008)Fujita, K., et al. Acta Neuropathol. 116(4):439-445(2008)Robledo, S., et al. RNA 14(9):1918-1929(2008)Glover, E.I., et al. Am. J. Physiol. Regul. Integr. Comp. Physiol. 295 (2), R604-R610 (2008) :Ma, X.M., et al. Cell 133(2):303-313(2008)

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$ 80.00
Cat# BP10275a
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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