|Other Accession||NP_001007246.1, NP_001541.2|
|Other Names||Interferon-related developmental regulator 1, Nerve growth factor-inducible protein PC4, IFRD1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal (By similarity).|
|Tissue Location||Expressed in a variety of tissues.|
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This gene is an immediate early gene that encodes aprotein related to interferon-gamma. This protein may function as atranscriptional co-activator/repressor that controls the growth anddifferentiation of specific cell types during embryonic developmentand tissue regeneration. Mutations in this gene are associated withsensory/motor neuropathy with ataxia. This gene may also beinvolved in modulating the pathogenesis of cystic fibrosis lungdisease. Alternate splicing results in multiple transcriptvariants.
Zhao, C., et al. J. Biol. Chem. 285(12):8552-8562(2010)Brkanac, Z., et al. Am. J. Hum. Genet. 84(5):692-697(2009)Gu, Y., et al. Nature 458(7241):1039-1042(2009)Guo, H., et al. J. Biochem. 141(5):635-640(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)
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