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IFRD1 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O00458 |
|---|---|
| Other Accession | NP_001007246.1, NP_001541.2 |
| Clone Names | 91013155 |
| Gene ID | 3475 |
|---|---|
| Other Names | Interferon-related developmental regulator 1, Nerve growth factor-inducible protein PC4, IFRD1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | IFRD1 |
|---|---|
| Function | Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand- induced signal (By similarity). |
| Tissue Location | Expressed in a variety of tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is an immediate early gene that encodes aprotein related to interferon-gamma. This protein may function as atranscriptional co-activator/repressor that controls the growth anddifferentiation of specific cell types during embryonic developmentand tissue regeneration. Mutations in this gene are associated withsensory/motor neuropathy with ataxia. This gene may also beinvolved in modulating the pathogenesis of cystic fibrosis lungdisease. Alternate splicing results in multiple transcriptvariants.
References
Zhao, C., et al. J. Biol. Chem. 285(12):8552-8562(2010)Brkanac, Z., et al. Am. J. Hum. Genet. 84(5):692-697(2009)Gu, Y., et al. Nature 458(7241):1039-1042(2009)Guo, H., et al. J. Biochem. 141(5):635-640(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)
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