|Other Names||Beta-tectorin, TECTB|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side Secreted, extracellular space, extracellular matrix. Note=Found in the non-collagenous matrix of the tectorial membrane|
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Provided below are standard protocols that you may find useful for product applications.
The genes for alpha-tectorin (MIM 602574) andbeta-tectorin encode the major noncollagenous proteins of thetectorial membrane of the cochlea.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)Deloukas, P., et al. Nature 429(6990):375-381(2004)Legan, P.K., et al. J. Biol. Chem. 272(13):8791-8801(1997)
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