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ATPBD3 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q7Z7A3 |
|---|---|
| Other Accession | NP_660275.2 |
| Clone Names | 91230221 |
| Gene ID | 90353 |
|---|---|
| Other Names | Cytoplasmic tRNA 2-thiolation protein 1 {ECO:0000255|HAMAP-Rule:MF_03053}, 277- {ECO:0000255|HAMAP-Rule:MF_03053}, ATP-binding domain-containing protein 3 {ECO:0000255|HAMAP-Rule:MF_03053}, Cancer-associated gene protein, Cytoplasmic tRNA adenylyltransferase 1 {ECO:0000255|HAMAP-Rule:MF_03053}, CTU1 {ECO:0000255|HAMAP-Rule:MF_03053} |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CTU1 {ECO:0000255|HAMAP-Rule:MF_03053} |
|---|---|
| Function | Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. |
| Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
References
Schlieker, C.D., et al. Proc. Natl. Acad. Sci. U.S.A. 105(47):18255-18260(2008)Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
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