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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   COASY Antibody (Center) Blocking peptide   

COASY Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q13057
Other Accession NP_001035995.1, NP_001035997.2, NP_079509.5, NP_001035994.1, NP_001035996.1
Clone Names 91216272
Peptide ID 91216272
Additional Information
Gene ID 80347
Other Names Bifunctional coenzyme A synthase, CoA synthase, NBP, POV-2, Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT, Dephospho-CoA kinase, DPCK, Dephosphocoenzyme A kinase, DPCOAK, COASY
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation.
Cellular Location Cytoplasm. Mitochondrion matrix. Note=The protein is mainly present in the mitochondrial matrix, probably anchored to the inner mitochondrial membrane, but is also present in cell lysate
Tissue Location Expressed in all tissues examined including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocyte. Lowest expression in peripheral blood leukocytes and highest in kidney and liver. Isoform 2 is expressed mainly in the brain.
Research Areas
Citations (0)

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Biosynthesis of coenzyme A (CoA) from pantothenic acid(vitamin B5) is an essential universal pathway in prokaryotes andeukaryotes. COASY is a bifunctional enzyme that catalyzes the 2last steps in CoA synthesis. These activities are performed by 2separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC2.7.7.3) and dephospho-CoA kinase (DPCK; EC, inprokaryotes (Daugherty et al., 2002 [PubMed 11923312]).[supplied byOMIM].


Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)Breus, O., et al. Biochem. Biophys. Res. Commun. 385(4):581-585(2009)Hamaguchi, M., et al. Jpn. J. Clin. Oncol. 38(11):734-742(2008)Nemazanyy, I., et al. Biochem. Biophys. Res. Commun. 341(4):995-1000(2006)Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)

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$ 80.00
Cat# BP10371c
Availability: In Stock
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