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AIF1 Antibody (N-term) Blocking PeptideSynthetic peptide
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| BP10449a | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
AIF1 Antibody (N-term) Blocking Peptide - Product info | |
| Primary Accession | P55008 |
| Other Accession | NP_001614.3 |
| Clone Names | 80102115 |
| Calculated MW | 16703 Da |
AIF1 Antibody (N-term) Blocking Peptide - Additional info | |
| Gene ID 199 | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
AIF1 Antibody (N-term) Blocking Peptide - Protein Information | |
| Name AIF1 | |
| Synonyms G1, IBA1 | |
| Function Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1 Binds calcium. Plays a role in RAC signaling and in phagocytosis May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation | |
| Cellular Location Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis | |
| Tissue Location Detected in T-lymphocytes and peripheral blood mononuclear cells | |
AIF1 Antibody (N-term) Blocking Peptide - Related products
AP10449a: AIF1 Antibody (N-term)
AP11202b: AIF1 Antibody (C-term)
BP10449a: AIF1 Antibody (N-term) Blocking Peptide
AT1077a: AIF1 Antibody (monoclonal) (M01)
AF1039a: AIF1 / IBA1 (isoform 1 and 3) Antibody
AIF1 Antibody (N-term) Blocking Peptide - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
AIF1 is thought to be involved in negative regulation ofgrowth of vascular smooth muscle cells, which contributes to theanti-inflammatory response to vessel wall trauma.
REFERENCES
Clancy, R.M., et al. Arthritis Rheum. 62(11):3415-3424(2010)Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Jia, J., et al. Pediatr. Res. 67(1):29-34(2010)Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :
