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AIF1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P55008
Other Accession NP_001614.3
Clone Names 80102115
Peptide ID 80102115
Additional Information
Gene ID 199
Other Names Allograft inflammatory factor 1, AIF-1, Ionized calcium-binding adapter molecule 1, Protein G1, AIF1, G1, IBA1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AIF1
Synonyms G1, IBA1
Function Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Cellular Location Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis
Tissue Location Detected in T-lymphocytes and peripheral blood mononuclear cells.
Research Areas
Citations (0)

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AIF1 is thought to be involved in negative regulation ofgrowth of vascular smooth muscle cells, which contributes to theanti-inflammatory response to vessel wall trauma.


Clancy, R.M., et al. Arthritis Rheum. 62(11):3415-3424(2010)Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Jia, J., et al. Pediatr. Res. 67(1):29-34(2010)Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :

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$ 80.00
Cat# BP10449a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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