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ABCD1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P33897
Other Accession NP_000024.2
Clone Names 80722005
Peptide ID 80722005
Additional Information
Gene ID 215
Other Names ATP-binding cassette sub-family D member 1, Adrenoleukodystrophy protein, ALDP, ABCD1, ALD
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ABCD1
Synonyms ALD
Function Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.
Cellular Location Peroxisome membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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ABCD1 is a member of thesuperfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- andintra-cellular membranes. ABC genes are divided into seven distinctsubfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). Thisprotein is a member of the ALD subfamily, which is involved inperoxisomal import of fatty acids and/or fatty acyl-CoAs in theorganelle. All known peroxisomal ABC transporters are halftransporters which require a partner half transporter molecule toform a functional homodimeric or heterodimeric transporter. Thisperoxisomal membrane protein is likely involved in the peroxisomaltransport or catabolism of very long chain fatty acids. Defects inthis gene have been identified as the underlying cause ofadrenoleukodystrophy, an X-chromosome recessively inheriteddemyelinating disorder of the nervous system.


Matsukawa, T., et al. Neurogenetics (2010) In press :Xie, H.H., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27(2):144-148(2010)Li, J.Y., et al. J. Neurol. Sci. 290 (1-2), 163-165 (2010) :Hour, T.C., et al. Int. J. Biol. Markers 24(3):171-178(2009)Shukla, P., et al. J. Child Neurol. 24(7):857-860(2009)

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$ 80.00
Cat# BP10454c
Availability: In Stock
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