|Other Accession||NP_001128726.1, NP_039236.1, NP_002575.1|
|Other Names||Paired box protein Pax-7, HuP1, PAX7, HUP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor playing a role in myogenesis through regulation of muscle precursor cells proliferation.|
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Provided below are standard protocols that you may find useful for product applications.
PAX7 is a member of the paired box (PAX) family oftranscription factors. Members of this gene family typicallycontain a paired box domain, an octapeptide, and a paired-typehomeodomain. These genes play critical roles during fetaldevelopment and cancer growth. The specific function of the pairedbox 7 gene is unknown but speculated to involve tumor suppressionsince fusion of this gene with a forkhead domain family member hasbeen associated with alveolar rhabdomyosarcoma. Three transcriptvariants encoding different isoforms have been found for this gene.
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Williamson, D., et al. J. Clin. Oncol. 28(13):2151-2158(2010)Xynos, A., et al. Stem Cells 28(5):965-973(2010)Edwards, T.L., et al. Ann. Hum. Genet. 74(2):97-109(2010)Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
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