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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   CF150 Antibody (Center) Blocking Peptide   

CF150 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8N884
Other Accession NP_612450.2
Clone Names 91201028
Peptide ID 91201028
Additional Information
Gene ID 115004
Other Names Cyclic GMP-AMP synthase, cGAMP synthase, cGAS, h-cGAS, Mab-21 domain-containing protein 1, MB21D1, C6orf150
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MB21D1
Synonyms C6orf150
Function Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. Catalysis involves both the formation of a 2',5' phosphodiester linkage at the GpA step and the formation of a 3',5' phosphodiester linkage at the ApG step, producing c[G(2',5')pA(3',5')p]. Has antiviral activity by acting as a key cytosolic DNA sensor, the presence of double- stranded DNA (dsDNA) in the cytoplasm being a danger signal that triggers the immune responses. Binds cytosolic DNA directly, leading to activation and synthesis of cGAMP, a second messenger that binds to and activates TMEM173/STING, thereby triggering type-I interferon production.
Cellular Location Cytoplasm, cytosol
Tissue Location Expressed in the monocytic cell line THP1.
Research Areas
Citations (0)

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The exact function of C6orf150 remains unknown.


Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Mungall, A.J., et al. Nature 425(6960):805-811(2003)

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$ 80.00
Cat# BP10510c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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