|Other Names||Zinc finger protein 197, Zinc finger protein with KRAB and SCAN domains 9, ZnF20, pVHL-associated KRAB domain-containing protein, ZNF197, ZKSCAN9, ZNF166|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in transcriptional regulation.|
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Provided below are standard protocols that you may find useful for product applications.
ZNF197 product belongs to the zinc finger proteinsuperfamily, members of which are regulatory proteins characterizedby nucleic acid-binding zinc finger domains. The encoded proteincontains 20 tandemly arrayed C2H2-type zinc fingers, aKruppel-associated box (KRAB) domain, and a SCAN box. Thistranscript turns over rapidly and contains 3' UTR AUUUA motifs,which are often a hallmark of rapid turnover. It is overexpressedin some thyroid papillary carcinomas. ZNF197 is located in acluster of zinc finger genes at 3p21. Two alternatively splicedtranscripts encoding different isoforms have been described.
Li, Z., et al. EMBO J. 22(8):1857-1867(2003)Gonsky, R., et al. Nucleic Acids Res. 25(19):3823-3831(1997)Calabro, V., et al. Hum. Genet. 95(1):18-21(1995)Pengue, G., et al. Hum. Mol. Genet. 2(6):791-796(1993)
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