CCDC8 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H0W5 |
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Other Accession | NP_114429.2 |
Clone Names | 91230188 |
Gene ID | 83987 |
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Other Names | Coiled-coil domain-containing protein 8, CCDC8 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CCDC8 |
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Function | Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696). Required for localization of CUL7 to the centrosome (PubMed:24793695). |
Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome |
Tissue Location | Widely expressed with low levels in spleen, skeletal muscle, small intestine, kidney and liver |
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Provided below are standard protocols that you may find useful for product applications.
References
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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